Cirrhosis with stomach pain may be related to spontaneous peritonitis, biliary tract infection, ascites, hepatocellular carcinoma, etc., which can be treated with medication, laparotomy and surgery. Cirrhosis patients with abdominal pain must be based on the location, degree, nature of pain and accompanying symptoms, comprehensive analysis of the cause of the targeted treatment, do not arbitrarily use painkillers, so as not to delay the condition. 1. Cirrhosis patients usually have decreased resistance and are prone to various infections, including spontaneous peritonitis, gastroenteritis, biliary tract infections, etc., which will cause abdominal pain, and we can consider applying sensitive antibiotics in sufficient quantity and course to help control the inflammation. 2. A large amount of ascites can also lead to abdominal distension and pain, diuretic drugs and albumin infusion can be used, and if necessary, abdominal paracentesis can be considered to release ascites in small amount and several times in order to reduce the symptoms. 3. Cirrhosis patients should also be alert to the possibility of hepatocellular carcinoma. If hepatocellular carcinoma exists, it can lead to pain in the right upper abdomen, and it is recommended to perform relevant examinations such as alpha-fetoprotein and liver imaging, and choose appropriate treatment plan according to the patient’s physical condition, such as surgery, radiofrequency ablation, interventional therapy, medication, etc. In addition, there are other causes that can lead to abdominal distension and pain. In addition, there are other reasons that may cause cirrhosis patients to experience abdominal pain, and they should go to the hospital in time to get a clear understanding of the cause and then under the guidance of the doctor to carry out targeted treatment.