The hardening of blood vessels after drip is phlebitis caused by damage to the endothelium of blood vessels, which can be improved by hot compresses on the skin and mucopolysaccharide polysulfate cream. The hardening of blood vessels after infusion is the intravenous use of stimulating drugs, is the endothelial damage caused by phlebitis, manifested as local redness, swelling and pain hardening. More often cause phlebitis drugs, quinolones, antifungal drugs, amiodarone and so on. Phlebitis caused by infusion is a self-limiting, can disappear on its own, elevate the affected limbs, skin swelling hot compresses can reduce swelling. The swelling is serious and can be improved by topical application of mucopolysaccharide polysulfate cream. Avoid using this blood vessel for another infusion. Long-term infusion is not recommended on the same blood vessel. The hardening of the blood vessel after the drip is recommended to intervene under the guidance of a doctor.