Calcium hydroxybenzenesulfonate has a certain therapeutic effect on varicose veins, but the specific efficacy varies from person to person. The pharmacological effects of the drug are: by reducing the permeability of the microvascular wall, reducing blood and plasma viscosity, reducing platelet hypercollageness, and thus preventing thrombosis, improving the flexibility of red blood cells, but also inhibit the microvascular hyperpermeability induced by vasoactive substances (histamine, 5-hydroxytryptophan, bradykinin, prostaglandin), promote the synthesis of collagen in the basement membrane, and thus play a role in the protection of microvessels. Therefore, the drug can be used in the treatment of varicose veins. Such as primary varicose veins – pain, leg pain, painful muscle spasms, sensory abnormalities, cyanosis of the hands and feet, purpuric dermatitis; state of varicose veins – chronic venous insufficiency (CVI), phlebitis and superficial thrombophlebitis, thrombophlebitic syndromes, varicose ulcers, varicose veins in pregnancy. The drug should be contraindicated in people who are allergic to the product, is not recommended for use in the first three months of pregnancy and lactating women, during the use of the drug occasionally nausea, stomach upset, heartburn, loss of appetite and other adverse reactions occur, the dose should be reduced, and if necessary, discontinue the administration of the drug. Specific medication should be carried out under the guidance of a specialist, not unauthorized use of drugs.