Definition: Cerebral infarction, also known as thrombotic cerebral infarction or cerebral thrombosis, accounts for about 80% of all strokes. II.Etiology: Thrombotic stroke is mainly caused by thrombosis or arterial occlusion due to atherosclerosis or arteritis of the main stem of cerebral arteries (e.g. internal carotid artery, middle cerebral artery, or basilar artery) or cortical branch arteries, which leads to interruption of localized cerebral blood flow and cerebral infarction, and the patients often suffer from TIA. (1) Atherosclerosis is the most common etiological cause of thrombotic cerebral infarction, and it affects the large and moderately sized elastic and muscular arteries, and susceptible sites include the beginning of the common carotid artery. (2) Various types of arteritis are the second leading cause of cerebral thrombosis. (3) Fibromuscular developmental abnormalities. It is an autosomal dominant disease and is more common in females. (4) Carotid or vertebral artery entrapment. This can be accompanied by bleeding into the vessel wall, blocking the lumen or predisposing to thrombosis and embolism. Diseases related to focal cerebral ischemia with thrombotic cerebral infarction include: 1, vascular diseases such as infectious diseases, giant cell arteritis, systemic lupus erythematosus, polyarteritis nodosa, syphilitic arteritis, AIDS, cerebral amyloidosis, venous sinus thrombosis. 2.Cardiac diseases such as thrombosis of the appendage, rheumatic heart disease, arrhythmia, endocarditis, heart valve repair after surgery. 3.Blood diseases such as thrombocytosis, erythrocytosis, leukocytosis, thromboembolic thrombocytopenic purpura.