Whether elevated creatinine can return to normal is usually determined by the cause of the condition. If the creatinine is elevated due to physiological reasons or acute kidney injury, the creatinine may return to normal or to the original level after removing the influencing factors. If the creatinine is elevated due to chronic kidney disease, with the progress of the disease, it may develop into uremia, at this time, creatinine usually can not return to normal.
Normal serum creatinine ranges from 53 to 106 μmol/L in men and from 44 to 97 μmol/L in women. Blood creatinine includes endogenous creatinine and exogenous creatinine. Endogenous creatinine is produced by creatine metabolism and is related to muscle volume and muscle activity; exogenous creatinine is closely related to diet, especially the consumption of heated animal muscle may lead to a rapid increase in blood creatinine levels.
Therefore, part of the creatinine elevation may be caused by the patient’s own high muscle content, or usually eat more meat and exercise, if the routine urine and urinary system ultrasound and other related examinations do not see any abnormality, clear kidney without obvious disease, such cases creatinine can return to normal.
If the patient’s creatinine is elevated due to acute kidney injury, creatinine may return to normal or to the original level after correcting the reversible causes. If the creatinine is elevated due to chronic kidney disease, with the progress of the disease, it may develop into uremia, at this time, creatinine usually can not return to normal.
If patients find that the creatinine is elevated, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.