STDs are disturbing people’s normal life and family harmony, people talk about “sex”, fear it like a “tiger”, many people suffer from STDs, ashamed to talk about it, resulting in the delay of the disease, resulting in some serious complications, there are also many STDs can be hereditary offspring or cause fetal malformation The actual fact is that there are a number of sexually transmitted diseases, such as syphilis, AIDS, herpes virus, gonococcus, chlamydia, mycoplasma and other microbial infections. 1, congenital syphilis untreated syphilis patients after pregnancy, syphilis spirochetes in the blood cause embryonic or fetal congenital syphilis infection can be as high as 75%-95% of the chances of its embryonic or fetal spread and placentitis caused by the spread of blood-borne syphilis spirochetes. Early congenital syphilis is diagnosed in infants under 2 years of age and is infectious and potentially life-threatening. The infant is immature or premature, has hemolytic anemia, hepatosplenomegaly, and occasional edema. Late-onset congenital syphilis appears in children older than 2 years of age, and about 2/3 or more have no obvious clinical signs but have persistently positive serology. The more classic manifestations of congenital syphilis include: (1) skin and mucosal damage: rhinitis, pharyngitis, blistering-herpetiform and papulosquamous lesions; (2) interstitial keratitis; (3) painless knee effusion; (4) deafness, dental or skeletal malformations; (5) neurosyphilis and cardiovascular malformations; 2. Human immunodeficiency virus (HIV, HIV) Infection HIV infection in infants and children is mainly transmitted by HIV-infected mothers through the placenta, when the fetus passes through the birth canal, and when breastfeeding after delivery. All newborns whose mothers are serologically positive for HIV can show signs of HIV seropositivity, but only about 30-45% of them actually have HIV infection; the rest are born with maternal antibodies that are passively transmitted from the womb. AIDS and HIV infection in children can cause: (1) craniofacial deformities and neurological damage; (2) chronic diarrhea, malnutrition and failure; (3) enlarged lymph nodes and parotid glands; (4) pulmonary disorders; (5) malignant tumors; 3. congenital herpes simplex virus infection The prevalence of herpes simplex virus (HSV) infection in women during pregnancy is about 1 to 2.5%. It can be transmitted to the fetus through the placenta and birth canal, and the infection rate of newborns is 1/5000-1/2500, although the proportion of infection is small, HSV infection causes a high rate of stillbirth. It can also cause viremia and viral encephalitis. The herpes of the cervix may also be related to cervical cancer. 4, condyloma acuminata Condyloma acuminata is transmitted mainly through sexual contact and mother-to-child transmission. The mother has the disease, during childbirth, the baby can be infected, the occurrence of infantile condyloma acuminata or laryngeal papilloma. Epidemiological data suggest a strong association between condyloma acuminata and genital cancer. A few genital and perianal warts appear and develop over time into carcinoma in situ or squamous cell carcinoma, especially cervical cancer, which have been confirmed by pathological examination. 5, gonococcal infection Neonates infected with gonococcus during the birth canal can cause neonatal gonococcal conjunctivitis. This is characterized by redness and swelling of the eyelids and a large amount of purulent discharge from the conjunctiva, which can occasionally be complicated by corneal perforation and blindness within a short period of time. Gonococci can be found in the secretions. Gonorrhea is also a common cause of infertility, ectopic pregnancy and pelvic infections. 6, genital candidiasis Genital candidiasis mainly refers to skin mucosal infections of the genitalia of Candida albicans. Male homosexuals can cause oral and anal Candida infections, while newborns can be infected through the mother’s birth canal causing thrush (Candida stomatitis). The rash is a scattered, variable-sized, single or multiple milky white film that peels off easily to reveal a bright red moist base, mostly on the oral mucosa, tongue, throat, gums, and lips. Those who have suffered from STDs should consult with relevant departments such as the Department of Dermatology and Venereology before requesting pregnancy. Most patients with STDs do not affect the next generation after being systematically cured in regular hospitals.