In general, bitter mouth and flatulence may be caused by gastrointestinal dysfunction caused by improper diet, gastric ulcer and other gastric diseases, etc. You can choose drugs such as Mosapride and other pro-gastrointestinal dynamics drugs, omeprazole and other drugs that inhibit the secretion of gastric acid to alleviate the symptoms. 1. Gastrointestinal stimulants: (1) Domperidone: mainly for the upper gastrointestinal tract, can promote gastric dynamics and gastric emptying, indigestion and gastroesophageal reflux disease and other diseases have good efficacy. (2) Mosapride: similar to itopride, cisapride, etc., such drugs can promote gastrointestinal peristalsis, but does not affect gastric acid secretion. (3) Trimethoprim maleate: it is a bidirectional drug to regulate the gastrointestinal tract, and has a certain inhibitory effect on patients with hyperdynamic gastrointestinal tract. For patients with insufficient gastrointestinal tract power, it has a certain promotion effect. 2. Inhibit gastric acid secretion drugs: you can choose cimetidine, rabeprazole, esomeprazole and other drugs to inhibit gastric acid secretion, can be treated with gastric ulcer, chronic gastritis and other underlying diseases, so as to promote the gastrointestinal tract’s digestive ability, reduce the occurrence of bloating, stomach pain and other indigestion symptoms. Bitter mouth and flatulence can also take microbial preparations such as Bacillus subtilis diphtheriae to relieve symptoms. All of the above medications should be used under medical supervision.