Diabetic nephropathy is the result of long-term development of diabetes, so sugar lovers need to clarify the screening methods for nephropathy in order to achieve early intervention and treatment. The common methods are usually 24-hour urine albumin quantification or random urine albumin to creatinine ratio (UmAlb/Ucr), urine routine, blood creatinine and urea nitrogen measurement, and kidney ultrasound. In the early stage of diabetic nephropathy, it usually only shows an increase in urine microalbumin quantification (<30mg/24h in normal people) or urine albumin to creatinine ratio (<30mg/g in normal people), while urine routine, serum creatinine and urea nitrogen can be normal, and the latter only starts to appear abnormal as the disease progresses. It is an easy way to screen for diabetes but in diabetic nephropathy there can be false negatives or false positives so measuring blood glucose is the main basis for diagnosis. Nuclear renal dynamic glomerular filtration rate (GFR), ultrasound measurement of increased kidney volume is consistent with early diabetic nephropathy. In uremia GFR decreases significantly, but there is often no significant reduction in kidney volume. In type 1 diabetes, diabetic nephropathy is almost certain in any patient with proteinuria in combination with diabetic retinopathy, especially after puberty. The main items we need to remember are: urine routine, blood creatinine and urea nitrogen measurement, and kidney ultrasound, which should be the routine checkups of. In addition, regular checkups, it is better to have a kidney checkup in three months or six months, if there are problems, timely treatment.