There are two main causes of diabetic nephropathy: the first is genetic susceptibility, some studies have shown that patients with diabetic nephropathy have a high chance of having diabetic nephropathy in their offspring, although these patients may also have good blood sugar control. The second point is that many patients with diabetes are found late, and when they are found to have diabetes, the high blood sugar level may have been there for many years. Therefore, the blood glucose level has already affected the kidney. There are also some patients who have diabetes, but their blood sugar has been in a high state for a long time and is not well controlled.