There is no clear clinical value for the number of hepatocyte necrosis in acute severe liver injury. Liver injury is not classified by the number of necrotic cells, but can be classified into mild, toxic and severe liver injury according to the degree of liver cell damage, clinical manifestations and whether there are corresponding complications. 1. Mild liver injury: symptoms are not obvious, liver function test is needed to check the abnormality of liver function, generally it will not have too much effect, and liver function can be restored by improving dietary habits. 2. Moderate liver injury: Due to the failure of timely and effective treatment for mild liver injury, there is a possibility of liver fibrosis, and the symptoms are more obvious, such as abdominal discomfort and loss of appetite. 3. Severe liver injury: critical symptoms, severe pain, very serious jaundice, confusion, prone to critical complications of liver failure, hepatic encephalopathy and so on. When the above clinical manifestations occur, it is necessary to go to the hospital in time to complete the relevant examinations, make a clear diagnosis, and standardize the treatment under the guidance of the doctor.