Clinical manifestations of Crohn’s disease

Crohn’s disease is a common clinical form of inflammatory bowel disease, and current research has found that it is a chronic inflammatory, granulomatous lesion of the intestine. Patients may present with intermittent abdominal pain, diarrhea, wasting, abdominal masses, or features of incomplete intestinal obstruction. Patients’ lesions tend to develop in the ileocecal canal of the body, and the lesions may involve the mucosa, submucosal muscle layer or even the entire intestinal canal, resulting in narrowing of the intestinal lumen, but less often intestinal perforation occurs, and some patients with severe disease may also be accompanied by ulcer perforation, resulting in the manifestation of a local abscess. The lesions can follow the segmental distribution of the intestinal canal, which can show the typical characteristics of oval goose stone during intestinal imaging. Due to the difficulty of curing this disease, severe patients have prolonged and recurrent attacks with poor prognosis.