There are several common causes of elevated alkaline phosphatase: 1. problems of the biliary system, such as primary biliary cholangitis, or bile duct cancer, gallbladder stones, cholecystitis, etc. 2. possible combination of cirrhosis or hepatocellular carcinoma, pancreatitis, etc. 3. if accompanied by elevated bilirubin and transpeptidase, consider biliary hepatitis or obstructive jaundice. 4. in children, elevation of this indicator is normal, indicating bone growth and development. 5. In the elderly, elevation of this index indicates osteoporosis. 6. It is also common in bone system problems, such as osteochondrosis and bone tumors. 7.