Alkaline phosphatase is clinically an important biochemical indicator, the enzyme is mainly distributed in the body’s tissues and fluids, with high content in bones, liver, gallbladder, small intestine and kidney, most of which are produced by bone cells. The main reasons for its high level: first, including metabolic abnormalities, such as sometimes seen in hepatitis, liver cancer, obstructive jaundice, obstructive jaundice, gallstones, etc., which generally cause cholestasis will basically lead to high alkaline phosphatase. Second, it is seen in the abnormal excretion of biliary tract, alkaline phosphatase is mainly produced by the liver, and after it is produced, it needs to be excreted by the liver through the biliary tract, it is seen in the common bile duct stones, tumors in the common bile duct cause abnormal excretion of bile, which will also cause high alkaline phosphatase. Third, see some drug alkaline phosphatase high, clinically common are antibiotics or barbiturates, can appear alkaline phosphatase high. Of course, the most important is to see the skeletal diseases, such as osteochondrosis, osteoporosis, systemic bone tumor metastasis or malignant bone tumor, etc., will appear alkaline phosphatase high.