The main difference between vulvar leukoplakia and vulvar vitiligo is that vulvar leukoplakia can develop mossy lesions and can be characterized by significant vulvar itching. Vulvar leukoplakia refers to white lesions on the vulva, including vulvar chronic simple moss and vulvar sclerosing moss. Typical symptoms are localized skin is dark red or pink, aggravated may become white, vulvar itching symptoms are serious, because of repeated scratching, will aggravate the local skin lesions, there may be chafing, ulceration, contracture and so on. Vulvar vitiligo is a disease caused by the destruction of melanocytes, the cause of which is not very clear and may be related to autoimmunity. The border of the lesion is more distinct, the surface is smooth and moist, the texture is normal, the patient usually has no obvious self-conscious symptoms, usually do not need to deal with.