Mannorrhea, the levonorgestrel intrauterine delayed release system, is valid for five years. The IUD should be removed within three to seven days after menstruation to exclude acute inflammation of the reproductive tract. After routine disinfection, a sterile orifice towel is placed, a vaginal speculum is placed, the vagina and cervix are disinfected again, and if there is a caudal filament at the cervical opening, the Mannorrhea IUD can be removed by gently pulling the caudal filament with oval forceps. If the filament is not at the cervical opening and has entered the uterine cavity, the IUD will need to be removed from the uterine cavity with a special IUD retrieval device or with foreign body forceps. After the operation, rest for one day and give anti-infection medication. After the IUD removal, intercourse and bathing are prohibited for two weeks, and if there is no pregnancy plan, other effective contraceptive measures should be taken. Manuel contains highly effective progesterone, which can treat excessive menstruation and dysmenorrhea caused by abnormal endometrial hyperplasia, endometriosis and adenomyosis on the one hand, and has a contraceptive effect on the other.