If the thickening of the synovium is due to inflammation, it may be cured by taking oral diclofenac sodium extended-release tablets as prescribed by the doctor. If the synovial thickening is caused by a tumor, the thickened synovial membrane can only be eliminated by surgery. Synovial thickening is mainly due to the patient’s joint area, after trauma or long-term weight-bearing activities, causing synovitis, inflammatory exudate and inflammatory changes, which stimulate the synovial membrane hyperplasia and thickening phenomenon. Patients can be treated with non-steroidal anti-inflammatory drugs, such as diclofenac sodium extended-release tablets or ibuprofen extended-release capsules, under the advice of a doctor. If the thickening of the synovial membrane is caused by a tumor, such as synovial sarcoma, patients are advised to remove the thickened synovial membrane through surgical treatment by completely removing the tumor from the synovial membrane area, and with radiotherapy and chemotherapy to remove the thickened synovial membrane. Patients with thickened synovial membrane should pay attention to sufficient rest, avoid overwork and strenuous activities. When sleeping, the affected limbs can be elevated, which can promote the dissipation of inflammation and blood return. Promptly consult the doctor, clarify the diagnosis and follow the doctor’s instructions for treatment.