Melanoma metastasized to lungs is generally difficult to cure, and conservative treatment is recommended to improve the quality of survival and prolong the survival period as much as possible. Melanoma has a high degree of malignancy, and metastasis can occur at early stage, so it needs to be detected and treated as early as possible. Early stage patients can be treated by local surgery to remove tumor tissues and surrounding lymph nodes. Patients’ melanoma has already metastasized to the lungs and distant metastasis has occurred, even if the primary tumor, metastatic tumor and surrounding lymph nodes are removed through surgery, it is difficult to guarantee whether it can be removed cleanly, which often leads to the rapid formation of new metastatic tumors, and most of the patients have poor physical condition, serious condition and more complications, so surgical resection of the tumor is already of little significance, and can only be used to prolong the life through conservative treatment. Currently for melanoma lung metastasis, chemotherapy and bioimmunotherapy are mainly used to inhibit tumor growth and metastasis, often using drugs such as dacarbazine, vincristine, cisplatin, bleomycin, pabolizumab, etc.; patients can also try to carry out the tumor genetic testing and use targeted drugs against mutations for treatment.