Urine routine leukocytes 2 +, indicating the presence of leukocytes in the urine, means that there may be a urinary tract infection, interstitial nephritis may be, need to undergo further examination to clarify the diagnosis. 1. Urinary tract infection: mainly divided into upper urinary tract infection and lower urinary tract infection, can also be divided into acute urinary tract infection and chronic urinary tract infection, will lead to the destruction of urinary epithelial mucosa, can be accompanied by leukocyte elevation, positive occult blood, etc., and at the same time more often accompanied by urinary frequency, urgency, painful urination, fever, chills, etc., and the urine culture more often than not, there is bacterial growth. 2. Interstitial nephritis: patients with interstitial nephritis may have positive urine leukocytes, negative urine culture, clinically known as aseptic leukocyturia, patients often have a history of taking medications, accompanied by positive urinary protein, renal function abnormalities, etc., no urinary discomfort. Urine leukocyte positive patients, it is necessary to go to the regular hospital to receive further examination, according to the results of the relevant examination, under the guidance of specialists to receive treatment.