Early symptoms of diabetes mellitus

Diabetes mellitus is a metabolic disease characterized by hyperglycemia, due to defective insulin secretion, or impaired insulin biological function, or a combination of both. Diabetes mellitus is insidious in its onset, and its early typical manifestations are three more and one less, i.e., more drinking, more eating, more urination and weight loss, but some patients are asymptomatic. 1. more drinking: people with diabetes mellitus often have the problem of thirst, more drinking, and increased urination, which leads to serious water loss in the body and cellular dehydration, aggravating the problem of hyperglycemia, and significantly increasing plasma osmolality, which forms a stimulus to the thirst center. Stimulation, thirst, drinking problems; 2, more food: patients are more hyperphagic, often feel hungry, and eat more. Due to insulin deficiency or insulin insensitivity, the body’s ability to utilize glucose decreases. Although the blood glucose in the body is high, the gap between the glucose concentration in the arteries and veins is small, and the tissues show a state of hunger, which in turn stimulates the feeding center and creates hunger and overeating problems. At the same time, the human body cannot make full use of glucose, most glucose needs to be excreted from urine, and the body is in a long-term semi-starvation state, so it can trigger hyperphagia; 3. Polyuria: diabetic people with high blood sugar content, the renal tubules cannot fully absorb the glucose filtered out by the glomerulus, and eventually osmotic diuresis occurs. Usually the higher the blood sugar of diabetic patients, the more urine sugar contained in the urine, and the greater the urine volume. However, when the blood sugar is moderately or mildly increased, the symptoms of polyuria are not obvious; 4. Weight loss: Due to the absolute or relative lack of insulin in the body, it is difficult for the body to make full use of the energy produced by glucose, so that the actual decomposition of protein and fat is enhanced, and too much is consumed in the body, which eventually leads to weight loss or even wasting; 5. Other symptoms: Some patients may have weakness, loss of vision, skin Itching and other symptoms, if the blood sugar is controlled during the treatment, the discomfort symptoms can be relieved. If patients have the above symptoms, they should go to the endocrinology department of the hospital for urine glucose measurement, blood sugar measurement and other related examinations to clarify the cause and control blood sugar in time.