In today’s society, the appearance of cranial defects is a common problem for patients in the rehabilitation period, most often seen after cerebral hemorrhage or traumatic brain injury, is a decompression measure to save lives during acute surgery, but with the recovery of the disease and intracranial hypertension, it is necessary to carry out cranial repair on the defective parts, to avoid accidental injury to the patient’s brain tissues, to reduce the psychological pressure, and to avoid the cerebral cortical folding back movement, to improve the blood supply of the cortex, and to facilitate hyperbaric oxygenation, and to facilitate hyperbaric oxygenation. It is favorable to the patient’s functional rehabilitation. Cranial bone repair surgery in the field of neurosurgery is not a very difficult surgery (because it does not need to move the brain), but patients should pay attention to the choice of cranial bone repair materials, a few large hospitals have chosen a new type of PEEK material as a cranial bone repair material. Our team has used PEEK material for many patients to implement surgery, the reason for choosing PEEK material as a cranial bone repair material, because PEEK material has a low density, insensitive to temperature, high tissue stability, so that it can be sterilized at high temperatures or radiation without deformation, etc., through the clinical feedback of the PEEK material has a transmissibility of rays, the results of CT and MRI will not have an impact on. PEEK materials are radiopaque and have no effect on CT and MRI results through clinical feedback. PEEK is an emerging material used in cranioplasty in the past 10 years, and has been gradually accepted by patients in China. It has also been recognized and well received by patients.