Antibiotics are almost the standard of care, while drinking adequate amounts of water and emptying the bladder several times to flush out the germs are recommended. Infections of the kidneys can also be mostly controlled with oral antibiotics, but severe cases require hospitalization, including anti-inflammatory treatment with fluids. Treatment of recurrent UTIs Some women have recurrent UTIs. If it occurs more than 3 times in a year, it is important to talk to your doctor about how to prevent or reduce these infections. Treatment options include long-term low-dose antibiotics, or single-dose antibiotics after sex, or self-treatment with antibiotics taken quickly when symptoms first appear. Over-the-counter medications One over-the-counter (OTC) medication, finapyridine (less commonly available domestically), is commonly used to control symptoms of pain, burning and irritation, but it is important to know that this medication only controls symptoms and does not treat the infection. It is most important to see your doctor to ensure that the bacteria causing the infection is treated. And know that it is common to take it because your urine will turn dark or orange.