According to the guideline summary, anti-hypertensive drugs, antidepressants, antipsychotics, anti-androgens, antihistamines, etc. can lead to male sexual dysfunction, which is detrimental to male sexual function. 1. Antihypertensive drugs: mainly diuretics and beta-blockers, such as furosemide, metoprolol, etc. Current research has found that the possible mechanisms of sexual dysfunction caused by antihypertensive drugs are drug-induced electrolyte disorders, decrease in neuromuscular sensitivity, and vascular smooth muscle relaxation. 2. Antidepressants and antipsychotics: Studies believe that these drugs act directly on specific areas of the brain, affecting sexual function through their effects on the central nervous system. Such as valium, phenobarbital, etc. 3. Antiandrogenic drugs: these drugs generally lead to a decrease in the level of sex hormones, which leads to a decline in sexual function, such as goserelin and other drugs. 4. Antihistamines: these drugs can lead to endocrine disorders, diabetes, hypertension, depression and other diseases, these diseases secondary effects on sexual function, resulting in sexual dysfunction. If you consider the decline in sexual function due to drugs, you should go to a regular hospital, the physician assessment, follow the physician’s advice on the adjustment of drugs, do not arbitrarily stop taking drugs.