The first aid methods for intussusception include general treatment, drug treatment, surgical treatment, etc. The specific first aid methods should be chosen according to the specific conditions of the patients, and there is no so-called “optimal” first aid method, so please follow the doctor’s instructions and standardize the treatment. 1. General treatment: For patients with short duration of intussusception (less than 48 hours), good general condition, no obvious dehydration and electrolyte disorders, air enema or water-soluble contrast enema can be carried out through ultrasound or X-ray real-time monitoring under the guidance of doctors. 2. Drug treatment: intestinal necrosis or intestinal perforation caused by intussusception may lead to abdominal infection and systemic inflammatory reaction. Patients with signs of infection should be treated with broad-spectrum antibiotics against common intestinal pathogens combined with anti-anaerobic drugs, such as cephalosporins and metronidazole under the guidance of doctors. 3. Surgical treatment: For infants and young children suspected of intestinal necrosis, peritonitis, failure of enema treatment, recurrent intussusception, and suspected organic intestinal pathology, caesarean section should be performed as a matter of urgency. Adult intussusception is mostly secondary to intestinal pathology, and caesarean section should also be performed when the diagnosis is clear. Once found, patients with intussusception should be given standardized treatment as soon as possible under the guidance of professional doctors to avoid delaying the condition.