High creatinine in kidney function indicates renal failure, which can be caused by acute factors, that is, acute renal failure, or chronic diseases, that is, chronic renal failure. The main causes of acute renal failure are blood loss after trauma or surgery, fluid loss after vomiting, diarrhea and heat stroke, connective tissue diseases such as systemic lupus erythematosus, allergies caused by drugs such as penicillin, tubular necrosis caused by drugs such as ibuprofen, urinary tract obstruction caused by urinary stones, prostate enlargement or tumors, etc. The main ones that can cause chronic renal failure are chronic glomerulonephritis, diabetic nephropathy, hypertensive nephropathy, purpura nephritis, polycystic kidney, uric acid nephropathy, etc. Therefore, it is necessary to clarify whether acute renal failure or chronic renal failure is found to have high creatinine in kidney function. Because acute renal failure in most cases can be cured, while chronic renal failure can not be cured, that is, the prognosis is not the same. Then actively search for the cause and clarify the next treatment plan.