Always waking up at four or five o’clock in the morning and not being able to sleep is considered a neurological disorder, a type of sleep disorder that falls under the category of early awakening. For this situation, patients are advised to improve their sleep from their own lifestyle as well as medications. For example, the patient should develop a regular routine, and can improve the symptoms of early waking through acupuncture and head massage in Chinese medicine. You can take oral long-acting sleeping pills to make the sleep time longer and reduce the number of early awakenings. You can improve your sleep by taking oral dexrazoxane, diazepam, eszopiclone, alprazolam, clonazepam, etc. Patients should also adjust their emotions. If the patient wakes up at four or five o’clock every day and has a lot of energy during the day, you don’t have to care too much and don’t worry too much. If it affects the daytime life, you have to make adjustments as mentioned above.