Reflux esophagitis of 4 years can be cured in most patients, but for those who develop cancer on the basis of reflux esophagitis, most of them cannot be cured. Reflux esophagitis refers to the decrease of peristalsis and emptying ability of the stomach, and the decrease of pressure at the lower end of the esophagus, which makes the stomach acid reflux upward and causes the damage of the esophageal mucosa, and it is recommended to make a clear diagnosis through gastroscopy. After suffering from reflux esophagitis, it is recommended to choose drug treatment, and also need to pay more attention to the daily life aspects of the intervention. After suffering from reflux esophagitis, it is recommended to use drugs to inhibit the secretion of gastric acid, protect the gastric mucosa and promote the power of treatment under the guidance of doctors, such as omeprazole, magnesium beryllium carbonate, mosapride and so on. It is recommended to follow the doctor’s instructions to take the medication in sufficient quantity and course of treatment. In addition, in the daily life is also to light mainly, for spicy, stimulating food try not to eat. For patients who have suffered from reflux esophagitis for 4 years, gastroscopy is needed to determine whether there are ulcers, erosion of the mucosa of the lower esophagus or even the possibility of cancer. Examination of the presence of severe atypical hyperplasia of the mucosa of the lower esophagus or glandular adenoepithelial hyperplasia, it is recommended that under the guidance of the doctor as soon as possible surgical treatment, surgery can also be cured, but if the malignant lesions can be treated to slow down the progress of the disease, but more can not be cured. Therefore, patients who have been suffering from reflux esophagitis for 4 years, whether they can be cured or not needs to be judged after the doctor’s interview, combined with the results of the relevant programs and examinations.