HPV52 is the high-risk type of cervical cancer. Most of the simple high-risk HPV52 positives can be cured by themselves. For women over 30 years old, dual screening with HPV and TCT is recommended. If TCT is negative, most simple HPV52 positives can be cured by themselves with proper exercise, so there is no need to worry. However, if HPV52 is persistently positive combined with TCT abnormality, treatment is required, which includes colposcopic cervical or local vaginal biopsy and subsequent treatment based on the gold standard of pathology. The birth of the cervical cancer vaccine is epoch-making as it can prevent cervical lesions and cervical cancer to a large extent.