Taking tenofovir for diarrhea can be alleviated by stopping the drug for observation or choosing other antiviral drugs (e.g., entecavir, etc.), medication, and hospitalization under the guidance of a doctor. 1. Stop taking the drug for observation or choose other antiviral drugs: After taking tenofovir with diarrhea, you can stop taking it under the advice of your doctor. Diarrhea is one of the side effects of tenofovir, and if the side effects are mild, you may not need to take targeted treatment; if the symptoms are more serious, you should seek medical help in time. If the symptoms are more serious, medical help should be sought. In addition, other antiviral drugs, such as entecavir, can also be changed under the guidance of the doctor. 2. Medication: The symptoms can be relieved by applying hot compresses to the abdomen and taking probiotics. Combined with the condition, if gastroenteritis exists, anti-infective drugs such as levofloxacin capsules should be taken on the advice of a doctor, and the amount of water consumed should be increased to replenish the body’s hydration during the treatment. 3. Hospitalization: If taking tenofovir for diarrhea is serious, you can go to the hospital to do stool routine and blood routine, to determine the triggering cause of the symptom, and then change the medication under the advice of the doctor. If tenofovir diarrhea can not be effectively improved, you should go to the hospital in time for examination and symptomatic treatment.