The most common cause of chest tightness can be seen in coronary artery disease and angina pectoris. The typical manifestation of coronary artery disease and angina is episodic precordial pain, which is characterized by a feeling of pressure, tightness, and suffocation, and the pain lasts for a short period of time, usually about 3-5 minutes, not more than 15 minutes. The pain is often associated with activity, eating, and emotional excitement, and rest or nitroglycerin can quickly relieve the symptoms. Some patients may present with soreness in both shoulders or both upper limbs, or with toothache and soreness in the jaw, with a feeling of tightness in the chest. It is recommended to go to the hospital immediately and perform an electrocardiogram. If you cannot catch the electrocardiogram at the onset of symptoms, it is recommended to perform an exercise plate test or 24-hour ambulatory electrocardiogram monitoring to find out if there is any myocardial ischemia.