Normally, urine pH is between 4.5 and 7.9. If there is low urine pH, i.e., urine pH shows acidic results, the harm brought depends on the etiology that leads to low urine pH: 1. The common cause is diabetic ketoacidosis, which will lead to low urine pH. Diabetic acidosis brings harm, such as patients will experience nausea, vomiting, coma and even death. 2. Urine pH caused by metabolic or respiratory acidosis Low urine pH, respiratory acidosis or metabolic acidosis can lead to respiratory muscle paralysis and even respiratory failure. 3, Severe diarrhea leads to low urine pH, severe diarrhea can lead to water loss, decreased blood pressure, and even shock and death. 4, Low urine pH is prone to the formation of kidney stones. Therefore, when low urine pH occurs, it is important to actively search for the cause and provide timely treatment.