Adult thalassemia is also known as impaired bead protein production anemia, and patients have symptoms such as anemia, hepatosplenomegaly, and jaundice. 1. Anemia: When there is a disorder of bead protein production, it will lead to impaired synthesis of red blood cells, and thus anemia occurs. 2. Hepatosplenomegaly: Thalassemia is an extravascular hemolysis, due to the cell shape and dysfunction, it will cause the spleen system to recognize the loss of erythrocyte function, so the spleen will phagocytose the erythrocytes, and this will lead to the hyperfunction of the liver and the spleen, and thus hepatosplenomegaly will occur. 3. Jaundice: Due to extravascular hemolysis, a large amount of free hemoglobin exists in the blood after cell lysis, which can lead to jaundice. Adults with thalassemia may also have other symptoms such as developmental abnormalities, weakness of limbs, respiratory difficulties, and should consult a doctor in time for a clear diagnosis and receive targeted treatment under the guidance of a physician.