There is no such thing as a cream that removes moles without leaving scars. Patients want to apply creams to play the role of mole removal, often accompanied by the appearance of scars. Because the application of mole removal creams, often have obvious corrosive effect, like hydroquinone cream can often bring patients local redness, swelling, pain, and the occurrence of blisters. Therefore, the current cream to remove moles is not the first-line treatment option for pigmented nevi. Currently, laser, liquid nitrogen freezing or surgical excision are the first recommended treatments for moles. Because these treatments can effectively control the patient’s wound. Therefore, patients often do not have obvious scars on the local skin, and these treatments are more mature and do not bring great pain to patients.