Hyaluronic acid is a good method to remove neck lines, and the patient’s neck muscles can be maintained smooth and no wrinkles will be formed after surgery, so it will not affect normal facial expressions. However, as a medical practice, its surgical operation may have certain risks, as follows: 1. Within 72 hours after hyaluronic acid injection, local skin may show transient erythema, edema, hard nodules, itching and bruises, most of which will subside on their own, while a few require emergency treatment; 2. Within a few days to a few weeks after injection, local infection, skin necrosis, skin color change and pigmentation may occur; 3. 3.Long-term risks: including displacement of hyaluronic acid filling, delayed hypersensitivity reaction, foreign body granuloma and scar formation, but generally very rare; 4.The effect of hyaluronic acid for neckline removal is not permanent, generally it can last about 1 year, and the maintenance time is related to the type of hyaluronic acid, patient’s own constitution and postoperative daily care. Therefore, several treatments are needed to achieve the ideal effect. Generally, one or more injections is a course of treatment, with an interval of 1 year each time; 5. The injection may show embolic symptoms, mainly local skin necrosis. In summary, candidates should choose the regular medical plastic surgery institutions for medical treatment, standardized surgical operation can effectively prevent the occurrence of risks.