Moderate obstructive sleep apnea syndrome means that the sleepiness caused by the disease affects the life, and the patient has the risk of sleep disorder and cardiovascular disease related to the breathing disorder, which can be treated with general treatment, etiological treatment, oxygen therapy, non-invasive ventilation therapy and surgery as prescribed by the doctor. 1. General treatment: patients should first pay attention to sleep hygiene and cultivate good sleep habits. In addition, they should quit smoking and drinking, and obese people should pay attention to weight loss. 2. Etiological treatment: patients suffering from moderate obstructive sleep apnea syndrome due to hypothyroidism can use thyroxine for replacement therapy; patients with acromegaly can have their lesions removed by surgery to improve obstructive sleep apnea syndrome. 3. Oxygen therapy: patients with indications for oxygen therapy should also be combined with continuous positive airway pressure ventilation, so as not to exacerbate the patient’s condition due to oxygen alone. 4. Non-invasive ventilation: Non-invasive ventilation is the treatment of choice to help adults with obstructive sleep apnea syndrome. 5. Surgery: Surgery is aimed at removing anatomical stenosis and enlarging the airway for different and obstructive areas, and the main surgical methods adopted include tracheotomy and tracheostomy, palatopharyngeal soft palatoplasty, and so on. After the diagnosis of moderate obstructive sleep apnea syndrome is confirmed, the patient should actively cooperate with professional physicians to implement individualized treatment plans, and follow the doctor’s instructions to standardize the use of medication and treatment.