Galibert first reported the application of percutaneous vertebroplasty for the treatment of patients with vertebral hemangioma in 1987, and then the technique was used for the treatment of vertebral compression fracture in osteoporosis with good results. In recent years, the number of domestic reports has gradually increased. In our department, percutaneous perforation vertebroplasty was used to treat 29 cases of 40 vertebral osteoporotic compression fractures from March to October 2003, with no complications, significant pain relief, and good postoperative recovery. I. Traditional surgical methods are not adapted to the needs of osteoporotic fractures Osteoporotic compression fractures of the crural vertebrae are most commonly seen in the elderly, often without a history of trauma or minor violence (e.g., bending, falling and sitting, etc.). Some patients have insignificant symptoms, but a significant number exhibit persistent low back pain or even severe pain, and are unable to sit or stand for long periods of time. Traditional treatments are ineffective and slow in relieving pain, and prolonged bed rest is prone to complications such as pneumonia and deep vein thrombosis of the lower extremities, which further aggravate osteoporosis and increase the risk of re-fracture, forming a vicious circle. The internal fixation of osteoporotic vertebrae is not reliable, and even if internal fixation is done, the fixation segments have to be very long, up to the level of chest 4, which is obviously unacceptable; it is not only traumatizing, but also often needs to take out the internal fixation, and the patient needs to suffer from two surgeries, and there are also defects of loosening and fracture of the internal fixation, and so on. However, the indications for percutaneous vertebroplasty for osteoporotic vertebral compression fractures are low back pain that has not been treated with medication, especially in patients who are more active or older. 1987, Galibert et al. first applied percutaneous vertebroplasty to treat vertebral hemangiomas. 1997, Lane first used it for osteoporotic vertebral compression fractures, and it was applied percutaneously, intradiscal injection of methyl methacrylate into the vertebral body, and the injection of the methyl methacrylate into the vertebral body. In 1997, Lane first used this technique in the treatment of osteoporotic vertebral compression fractures, injecting methyl methacrylate (PMMA) into the vertebral body percutaneously and via the pedicle, without any complication and with obvious pain relief. In recent years, this technique has been rapidly popularized in Europe and the United States, mainly for the treatment of vertebral compression fractures and vertebral metastases caused by vertebral osteoporosis, with obvious effects. Second, the surgical experience of percutaneous vertebroplasty 1, the surgeon should be carried out by an experienced crural surgeon, who is required to have skilled crural surgical techniques and rich experience in vertebral root puncture, and good imaging equipment, which is the basis for the success of the puncture, and the key to the success of the surgery. 2, the choice of surgical position, the use of prone position for percutaneous vertebroplasty. This position is convenient for operation and easy for pedicle root puncture, and should be used as much as possible. It is necessary to train the patients in the prone position before surgery, and those who cannot finish the surgery in the prone position should be changed to the lateral position. 3, bone cement modulation can not be too dry, too hard or too thin not shaped, too dry syringe can not be pushed in, too thin injection will be the vertebral body cancellous bone source of bleeding flushed out or can not be cured, increasing the chance of pulmonary embolism. Whether to add barium and tungsten powder into the bone cement to enhance its X-ray light-blocking property and ensure the safe and direct injection of bone cement under fluoroscopy, there are different opinions at home and abroad; the purpose of adding barium and tungsten powder is mainly to enhance the development of the bone cement when injecting the bone cement to prevent the extravasation of the bone cement and the accidental penetration of the bone cement into the abnormal peripheral venous blood vessels of the vertebral body, which may lead to the complication of pulmonary embolism. Complications of pulmonary embolism are rare. It has been suggested that pulmonary embolism is caused by the puncture into the perivertebral vein and the misplacement of bone cement into the venous vessels. The exact mechanism of pulmonary embolism is unclear. As long as the vertebral body is punctured accurately during the operation, coupled with the continuous and close supervision during the intraoperative injection of bone cement, extravasation of bone cement and accidental entry of bone cement into the perivertebral venous vessels can be prevented. Prevention Fractures should be actively prevented in middle-aged and elderly women, and the reoccurrence of fractures should be actively prevented and treated even more so after a fracture has occurred. It is generally believed that the first fracture is an important signal, and bone density test can be carried out after the fracture; 2 weeks after the treatment of the fracture itself, a drug to inhibit bone resorption plus VitD and calcium can be applied selectively according to the individual situation; appropriate exercise for muscle strength can be carried out; and the treatment of other diseases can be carried out actively, and so on. Further observation is needed to determine when and with what kind of medication the best prevention and treatment effect is after osteoporotic fracture. The present study is a preliminary observation of first-time fracture cases in each group, and further reports will be needed for a longer period of time and follow-up of more cases.