The skull is a very important group of bone tissue in the human body that plays an important role in protecting, supporting and backing up the brain and head and face. Therefore, if damage occurs to the skull, then it will seriously damage human health, and even life-threatening. Therefore, cranial defects must be able to occur and require prompt cranial repair. After cranial defects are repaired, many patients will be more concerned about the symmetry of the two sides after cranial repair? This involves the question of whether the cranial repair material is able to mold well. In the thousands of years of development of cranial bone repair, people have used a variety of cranial bone repair materials, countless, gold, silver, aluminum, lead, platinum, tantalum, stainless steel and other metal materials, celluloid, methacrylic resin, polyethylene, silicone rubber, coral, ceramics, hydroxyapatite and calcium phosphate cement and other non-metallic materials, but these materials are not good shape effect. Even the titanium mesh material, which is widely used in clinical practice, often requires the surgeon to modify the shape of the material during surgery, which is often unsatisfactory and time-consuming. To say that the shape effect is better, but also count the latest type of polyether ether ketone PEEK material. This material is needed before the operation on the patient’s head CT scanning, collection of three-dimensional data, and then according to the real data for three-dimensional reconstruction, 3D printing to complete the PEEK material molding. During the operation, the PEEK material can be accurately anastomosed to the bone window, and good symmetry can be achieved on both sides of the skull after repair. In addition, various other properties of PEEK material are also comparable to autologous skull, which is an excellent cranial bone replacement material, and is widely praised by the medical community and patients.