Without regular antiviral medication, hepatitis B virus replication will increase day by day. During the onset of abnormal liver function, the virus will replicate every 16 hours. Hepatitis B virus replication usually occurs when the hepatitis B DNA is elevated, and the higher the value of hepatitis B DNA, the more active the virus replication. Because the liver of patients with minor triple positive has a relatively strong compensatory capacity, it is often not easy for patients to find out. Since this kind of patients is due to the destruction of liver cells by hepatitis B virus leading to impaired liver function, therefore, it is necessary to carry out quantitative testing of hepatitis B virus DNA in time, and if the viral load in the body is higher, it is necessary to carry out antiviral treatment, and the commonly used antiviral medicines include entecavir, tenofovir, and so on. Timely liver-protecting treatment is needed, and commonly used liver-protecting drugs include diammonium glycyrrhizinate, compound glycyrrhizinate tablets, and so on. If the replication of hepatitis B virus is higher than one day, the patient should go to the hospital for examination and treatment in time. Drugs need to be used under the guidance of a professional physician, and should not be used arbitrarily on their own.