When a urine test is performed, a plus sign for vitamin C should not normally appear. If some patients show a plus sign for vitamin C, this may be related to the patient’s metabolic disease, as well as say eating too much food containing vitamin C as well as vegetables, and taking a lot of vitamin C. Because vitamin C is water soluble and easily appears in the urine, it does not have much clinical significance. If the urine test for vitamin C a minus sign is present in the case of a urinary tract infection, but the infection mainly depends on the level of white blood cells, so simply a minus sign is not very significant either. If the urine test vitamin C a plus sign and a minus sign appear at the same time is not clinically significant, it should be a normal phenomenon.