The causes of leg swelling after breast cancer chemotherapy include albumin reduction, sodium retention, angioneurotic edema and so on. Lower albumin can be caused by supplementing human albumin, sodium retention can be caused by applying diuretics, and vasoneurotic edema can be caused by using dexamethasone and other anti-allergic drugs. 1. Decrease of albumin: after chemotherapy, albumin can be decreased due to malnutrition, or it can be decreased due to liver function damage after chemotherapy, no matter which kind of albumin decreases, it can lead to leg swelling after chemotherapy, in this case, it is necessary to strengthen the nutrition, and at the same time, it can be treated with intravenous infusion of human blood albumin. 2. Water-sodium retention: water-sodium retention can occur after chemotherapy due to the large amount of intravenous infusion, such as the application of high-dose cisplatin often need hydration diuresis to reduce renal toxicity, when the infusion of more fluid may cause post-chemotherapy swelling of the legs, in this case, you can apply furosemide injection diuresis to reduce swelling. 3. Angioneurotic edema: some chemotherapeutic drugs have the side effect of angioneurotic edema, such as paclitaxel, docetaxel, etc., which are mostly related to allergic factors, and dexamethasone and other drugs can be applied to help reduce the side effect. There may be other reasons for post-chemotherapy edema of breast cancer, such as adriamycin, paclitaxel and other drugs can lead to decreased cardiac function, followed by post-chemotherapy leg swelling, which can be treated symptomatically by applying diuretics, beta-blockers and other drugs. It is recommended to follow the doctor’s instructions to improve the examination, to clarify the cause, and to actively treat it. Please strictly follow the doctor’s prescription for medication, and do not use medication on your own.