During pregnancy, pregnant women are usually advised to take appropriate supplements of calcium, vitamins and minerals, including folic acid and vitamin B12. This is because with the growth and development of the fetus, the demand for nutrients by pregnant women increases significantly. If the supply of calcium and other nutrients is insufficient, pregnant women may be more prone to the clinical manifestation of muscle twitching due to the lack of calcium in the body. In addition, due to the lack of calcium, the development of the fetus, especially bone development, may be affected to a certain extent, the probability of rickets after birth may be higher. However, not all pregnant women who do not take calcium supplements will experience such symptoms. Appropriate increase in dietary intake of calcium-rich foods can also play a better nutritional and protective role. However, if the nutrient intake is insufficient, it is recommended that appropriate supplementation of calcium, vitamins, as well as folic acid, vitamin B12, etc., to be able to correct the lack of minerals in the body, including a series of nutritional problems such as anemia, can effectively reduce the pregnant woman during pregnancy, the possibility of complications such as lower limb muscle pain, but also conducive to the growth and development of the fetus.