General anesthesia surgery in early pregnancy may have an effect, mainly the effect of anesthesia on the embryo, may lead to miscarriage, fetal malformation and so on. General anesthesia surgery in early pregnancy may have a certain impact on fetal growth and development, and the type of anesthetic used, as well as the dose of the drug has a certain relationship. Try not to choose general anesthesia surgery during pregnancy, if there are special circumstances, must choose general anesthesia surgery, should be after the operation, regular check the fetal growth and development. Generally at about 16 weeks of pregnancy to do Down’s syndrome screening, if necessary, also need to do amniocentesis test, to determine whether the fetus is growing and developing well.