Pancreatic head occupation may be congenital hereditary disease pancreatic cystic fibrosis, or pseudocyst of pancreatic head caused by acute and chronic inflammation, or pancreatic head cancer caused by various factors such as smoking, exposure to carcinogenic substances, long-term high-protein and high-fat diet, cell gene mutation and so on. 1. Pancreatic cystic fibrosis: it is an autosomal recessive disease, the pancreas may have different degrees of atrophy and steatosis, multiple cysts can be seen in the pancreas, and the cysts may be manifested as pancreatic head occupancy when they occur in the pancreatic head area. 2. Pseudocyst of pancreatic head: the pancreas can be stimulated by acute and chronic inflammation, which can lead to extravasation of pancreatic fluid and wrapping of inflammatory tissues in the surrounding, forming pseudocysts or masses, which can also be manifested as pancreatic head occupancy when occurring in the pancreatic head area. 3. Pancreatic head cancer: Pancreatic head cancer is a malignant tumor of pancreas, the etiology of which is not yet completely clear. It is believed to be related to smoking, exposure to carcinogenic substances, long-term high protein and high fat diet, cell gene mutation and other factors, and it can be manifested as pancreatic head occupancy on imaging. Pancreatic head occupation is an imaging description, the specific nature and cause of the disease need further analysis and examination, so it is recommended that the patient under the guidance of the doctor to clarify the cause of the disease and standardize the treatment.