Knee protruding a bone may have the following conditions: 1, bursitis, prolonged friction, compression may lead to inflammation at the knee bursa, bursitis constantly stimulate the surrounding muscle tissue, may lead to muscle swelling, pain, similar to the bone. Treatment may include Celecoxib capsules for oral pain relief, cefaclor capsules for anti-inflammation, and physical therapy such as herbal compresses and herbal fumigation to relieve symptoms. 2. Osteomalacia, if the knee joint has been exposed to cold for a long time, it may lead to osteomalacia and calcification, forming hard nodes at the knee joint, which are generally asymptomatic and do not require treatment. 3. Fracture deformity healing, if there is a history of traumatic fracture at the knee joint, the bone scab may grow during the fracture Poor position or premature stress can lead to abnormal healing of the fracture and may also have protrusion at the knee joint. If asymptomatic, periodic review and monitoring should be performed. If pain is present, a lofendione extended-release tablet may be given for pain relief.