If a woman’s menstruation is usually quite regular, and at the age of 20, she suddenly stops menstruating for half a year, the following possibilities are mainly taken into consideration in this case: firstly, it is that the woman has experienced premature failure of the ovaries, so her menstruation stops. The patient is often accompanied by some perimenopausal manifestations such as hot flashes and sweating, and at the same time will be accompanied by vaginal dryness. Through the examination of sex hormone six can be clearly diagnosed. Secondly, it is necessary to consider that the patient’s menstruation stops due to pregnancy. The patient has menopause for 6 months, and all of them have abdominal bulge and fetal movement, which can be clearly diagnosed through ultrasound. Third, the patient has endometrial damage and adhesion of the cervical canal, which leads to menstrual arrest. In this case, the patient has a history of abortion, scraping and other uterine operations, or a history of acute endometrial inflammation, which can be clearly diagnosed by hysteroscopy. Fourthly, patients with stress, emotional tension or excessive dieting, weight loss, etc. affect the hypothalamus pituitary and ovarian axis, resulting in menstrual failure.