High pressure 170mmHg low pressure 90mmHg belongs to grade 2 hypertension, there is no so-called “best” medicine, according to the patient’s situation, can be used in combination with amlodipine and valsartan and other treatments. Grade 2 hypertension refers to systolic blood pressure ≥ 160mmHg or diastolic blood pressure ≥ 100mmHg, high pressure 170mmHg low pressure 90mmHg belongs to the category of grade 2 hypertension, it is recommended to use two antihypertensive drugs for treatment in combination with a strict low-salt diet and improvement of lifestyle. Common types of antihypertensive drugs include dihydropyridine calcium channel antagonists (CCBs) such as amlodipine, angiotensin receptor inhibitors (ARBs) such as valsartan, angiotensin-converting enzyme inhibitors (ACEIs) such as Benadryl, and diuretics such as hydrochlorothiazide. Commonly used combination regimens include dihydropyridine CCB + ARB/ACEI/thiazide diuretics, such as amlodipine and valsartan/benazepril/hydrochlorothiazide, etc.; others include ACEI + thiazide diuretics, such as benazepril and hydrochlorothiazide combined. It is recommended that the choice of combination regimen be made under the guidance of a cardiologist, and the medication should be administered as prescribed, with long-term monitoring of blood pressure control.