Atrophic gastritis is a pathological change characterized by atrophy of the epithelium and glands of the gastric mucosa, a decrease in number, thinning of the gastric mucosa, thickening of the mucosal base, or with pyloric glandular hyperplasia and intestinal glandular hyperplasia, or with atypical hyperplasia. The symptoms of atrophic gastritis lack specificity and are not completely consistent with the extent of the lesion, and some patients may have no obvious symptoms. Some patients may present with discomfort, fullness, vague pain, burning pain in the upper and middle abdomen, with no rhythmicity of pain, or with indigestion such as loss of appetite, belching, acid reflux, and nausea. The mucosa is granular, with blood vessels revealed, grayish color, and small folds. It is often accompanied by erosion or with bile reflux. Signs are not obvious, and sometimes there is light pressure pain in the epigastrium. Atrophic gastritis combined with pernicious anemia often has generalized weakness, fatigue, may appear obvious anorexia, weight loss, anemia, while digestive symptoms can be insignificant. The treatment of atrophic gastritis is based on dietary regimen and no special treatment is needed for asymptomatic patients, while those with symptoms should be given standardized medication under the guidance of a doctor. Therefore, patients with atrophic gastritis do not necessarily have symptoms and therefore cannot rely solely on symptomatic performance to confirm the diagnosis; those with symptoms should go to the hospital for standardized examination to confirm the diagnosis and treatment under the guidance of a physician in a timely manner.