Throat discomfort may be caused by heart disease, but it is not a unique symptom of heart disease, need to improve the electrocardiogram, coronary angiography and other related tests for differential diagnosis. Heart disease, such as coronary heart attack can appear throat discomfort, myocardial ischemia can appear chest pain symptoms, some patients can reflex throat discomfort. The symptoms of throat discomfort are relatively common in clinical practice, and common causes include respiratory tract infections, bacterial or viral infections that can lead to inflammation of the throat, manifesting as throat discomfort. Heart disease causing throat discomfort is relatively rare, and a heart attack cannot be definitively diagnosed through this symptom. Patients with discomfort in the throat should undergo relevant examinations, and patients with suspected heart disease should go to the hospital in a timely manner, under the guidance of the physician to improve the electrocardiogram, coronary arteriography and other relevant examinations, to make a clear diagnosis and then give treatment.