Three months after a leukemia transplant is considered past the danger period. Graft-versus-host disease occurs after leukemia transplantation and can usually be categorized as acute graft-versus-host disease and chronic graft-versus-host disease. As the name suggests, acute graft-versus-host disease tends to be more acute, more severe, and more dangerous. Acute graft-versus-host disease often occurs within three months of transplantation. So if you get through the three months after a leukemia transplant safely, you’re relatively past the danger period. GVHD requires immunosuppressive therapy, including tacrolimus, cyclosporine, etc. During treatment, the amount of immunosuppressant drugs and the number of combined drugs should be adjusted according to the severity of the patient’s graft-versus-host disease. The specific use of drugs need to be carried out under the guidance of a physician.