What drugs can be taken for severe constipation in the elderly: 1. volumetric laxatives can be taken, represented by methylcellulose, which can be taken for a long time without obvious toxic side effects. 2. osmotic laxatives can be used to improve constipation in the elderly, represented by compound polyethylene glycol electrolyte dispersion, lactulose, etc. 3. stimulating laxatives can also be applied to improve constipation in the elderly, represented by aloe vera, senna, but this drug can damage the neurons of the intestinal wall and cause colonic melanosis. 4. This kind of drugs can damage the neurons of the intestinal wall and cause colonic melanosis, so it is not suitable for long-term application. 4.Probiotics can be added to improve the environment of the intestinal cavity and thus improve constipation. 5.The application of gastrointestinal power can also improve the constipation of the elderly.