There are many reasons that cause the baby to stop developing in the womb, congenital deficiencies or the influence of adverse factors later in life may lead to abnormal development, such as chromosomal abnormalities, immune factors, infectious factors, luteal insufficiency, and then there are adverse environmental factors, maternal systemic diseases and sperm abnormalities that may lead to fetal failure to develop. It is advisable to have a comprehensive examination before pregnancy, including eugenic virus test, routine medical examination, gynecological examination, risk assessment of genetic diseases, etc., so as to exclude as much as possible the adverse influencing factors and ensure the healthy development of the fetus.